Role of Antioxidants and Natural Products in Inflammation

Palanisamy Arulselvan, 1 , * Masoumeh Tangestani Fard, 2 Woan Sean Tan, 1 Sivapragasam Gothai, 1 Sharida Fakurazi, 1 Mohd Esa Norhaizan, 3 and S. Suresh Kumar 4


Inflammation is a comprehensive array of physiological response to a foreign organism, including human pathogens, dust particles, and viruses. Inflammations are mainly divided into acute and chronic inflammation depending on various inflammatory processes and cellular mechanisms. Recent investigations have clarified that inflammation is a major factor for the progression of various chronic diseases/disorders, including diabetes, cancer, cardiovascular diseases, eye disorders, arthritis, obesity, autoimmune diseases, and inflammatory bowel disease. Free radical productions from different biological and environmental sources are due to an imbalance of natural antioxidants which further leads to various inflammatory associated diseases. In this review article, we have outlined the inflammatory process and its cellular mechanisms involved in the progression of various chronic modern human diseases.