Disease Prevention

Comparative computational study of interaction of C60-fullerene and tris-malonyl-C60-fullerene isomers with lipid bilayer: relation to their antioxidant effect

Marine E Bozdaganyan 1, Philipp S Orekhov 1, Alexey K Shaytan 1, Konstantin V Shaitan 1

Abstract

Oxidative stress induced by excessive production of reactive oxygen species (ROS) has been implicated in the etiology of many human diseases. It has been reported that fullerenes and some of their derivatives-carboxyfullerenes-exhibits a strong free radical scavenging capacity.